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ACGH Detects Copy Number Variation with Similar Resolution to PacBio Sequencing Approaches

ABSTRACT: This study examines genomic copy-number variation between two African cichlid species through array comparative genomic hybridization. Probe level hybridization ratios were compared to copy number variation identified in Illumina and Pacific Biosciences genome assemblies from both species. Array comparative genomic hybridization was performed with 3 samples (1 replicate array setup) of genomic DNA from Maylandia zebra vs. Orechromis niloticus XX clone genomic DNA from University of Stirling clonal lines.

ORGANISM(S): Neolamprologus brichardi Maylandia zebra Pundamilia nyererei Haplochromis burtoni Oreochromis niloticus

PROVIDER: GSE141976 | GEO | 2019/12/14

REPOSITORIES: GEO

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