Therapeutic IDOL reduction ameliorates amyloidosis and improves cognitive function in APP/PS1 mice
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ABSTRACT: An antisense oligonucleotide (ASO) against E3 ubiquitin ligase IDOL in the brain significantly decreased Aβ pathology, and improved spatial learning and memory in APP/PS1 mice.
ORGANISM(S): Mus musculus
PROVIDER: GSE142535 | GEO | 2019/12/24
REPOSITORIES: GEO
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