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PIM kinase inhibition in HCC xenograft

ABSTRACT: Human HCC cell line, MHCC-97L, was subcutaneously injected to BALB/c nude mice. Two weeks post injection, mice were randomised to receive vehicle or PIM447 (60mg/kg) by oral gavage three times a week for two weeks. Total RNA was extracted from the tumor xenograft (Vehicle, n=2; PIM447, n=2) and subjected to RNA sequencing. Expression profiling of the tumors between vehicle control and PIM447 treated groups was compared.

ORGANISM(S): Homo sapiens

PROVIDER: GSE142871 | GEO | 2020/06/03

REPOSITORIES: GEO

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