Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of human neural crest cells

ABSTRACT: The expression profiles of five human trunk level neural crest cell lines were determined on Affymetrix chips HG U133 Plus 2.0.

ORGANISM(S): Homo sapiens

PROVIDER: GSE14340 | GEO | 2009/08/26

SECONDARY ACCESSION(S): PRJNA111523

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcription profiling of human neural crest cells

Project description:The expression profiles of five human trunk level neural crest cell lines were determined on Affymetrix chips HG U133 Plus 2.0. Experiment Overall Design: Total RNA was extracted from a confluent 10 cm dish of hNCC (lines N1-N5) from five human embryos at 26-32 dpf (Carnegie stages 12 & 13).

2009-09-13 | E-GEOD-14340 | biostudies-arrayexpress

Expression profiling of neuroblastic tumors

Project description:The expression profiles of 64 neuroblastic tumors (mainly neuroblastoma) were determined on Affymetrix chips HG U133 Plus 2.0.

2008-10-16 | GSE12460 | GEO

Colorectal adenocarcinomas and matched normal colonic tissues

Project description:Five colorectal adenocarcinomas and matched normal colonic tissues were analyzed with Affymetrix HG-U133-Plus-2.0 microarrays. Two labs independently generated microarray data with the same array platform on the same biological samples.

2012-10-03 | GSE41328 | GEO

Gene expression data on human keratinocytes with knockdown or overexpression of SNAI2

Project description:1. Keratinocytes infected with retroviruses expressing control or SNAI2 shRNAs were cultured in growth medium and Affymetrix HG-U133 plus 2.0 arrays were used to determine global gene expression profiles. 2. Keratinocytes infected with retroviruses overexpressing LACZ or SNAI2 were cultured in growth medium and Affymetrix HG-U133 plus 2.0 arrays were used to determine global gene expression profiles.

2014-10-15 | GSE55269 | GEO

Identification of cranial-specific neural crest genes by comparative transcriptomics

Project description:We employ RNA-seq of FACS sorted cell populations to identify genes that are enriched in cranial neural crest in relationship to the trunk. Transcriptional profiling of delaminating cranial and trunk neural crest subpopulations.

2016-06-24 | E-GEOD-75125 | biostudies-arrayexpress

Microarray analysis of Polyoma Small T expressing U2OS cell lines

Project description:In order to understand which pathways are involved and what genes are affected when small T is expressed in mammalian cells, we carried out microarray analaysis in these cell lines Total cellulatr RNA was isolated at 20 hrs after doxycycline addition in samples 2,4 and 6 (+DOX), and was subjecyed to microarray analysis using Affymetrix Human Genome U133 Plus 2.0 (HG-U133_Plus_2) chips.

2020-04-29 | GSE149525 | GEO

Affymetrix striptease

Project description:new and stripped chips Keywords: reuse of Affymetrix GeneChips U133 Plus 2.0

2005-08-20 | GSE2833 | GEO

Trunk neural crest gene MOXD1 affects embryonic development

Project description:Ectoderm-derived neural crest is a transient structure arising during early embryogenesis in vertebrates. Neural crest consists of four derivatives based on their anterior- to posterior location along the body axis; cranial, vagal, trunk and sacral, respectively. We recently showed that trunk neural crest-specific gene MOXD1 functions as a tumor suppressor in trunk neural crest-derived childhood cancer form neuroblastoma and is essential for proper development of healthy adrenal glands. However, the role of MOXD1 during early embryogenesis is not known. Here, we conditionally knocked out MOXD1 in trunk neural crest cells before they become lineage-committed, using a CRISPR/Cas9 approach in chick embryos. Assessment of embryo growth showed that knockout of MOXD1 delayed development with knockout embryos being smaller. RNA sequencing of trunk-derived neural crest cells from control and knockout embryos showed enrichment of genes connected to gland development, copper ion metabolism and neuroblastoma progression. In conclusion, MOXD1 is important during early and prolonged embryonic development with effects on gland formation, possibly mediated via its role in copper metabolism.

2023-09-13 | GSE242700 | GEO

Distinct phenotype and function of anergic CD8+ T cells produced by Treg-cell suppression.

Project description:Four conditions of cultured CD8+ T cells were analyzed with Affymetrix HG-U133-Plus-2.0 microarrays.

2014-11-11 | GSE63129 | GEO