Colon, rectum and rectal tumor organoids. Effects of calcitriol (active form of Vitamin D) treatment

ABSTRACT: We have established three-dimensional (3D) organoids from healthy colon and rectum tissue and from tumor tissue of patients with rectal cancer. Global transcriptomic analyses reveal differences in gene expression between these stem cell-derived cultures and distinct response to vitamin D.

ORGANISM(S): Homo sapiens

PROVIDER: GSE143782 | GEO | 2020/09/08

REPOSITORIES: GEO