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Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1

ABSTRACT: This study is to identify downstream targets of homeobox gene CDX1. The study assayed the expression of 2 pairs of stably transfected colorectal cancer cell lines: The CDX1 nonexpressing CRC cell line HCT116 was stably transfected with either CDX1 cDNA in the pRC/CMV expression vector (HCT116-CDX1) or with vector control (HCT116-Vec). The CDX1-expressing CRC cell line LS174T was similarly transfected with either a pSilencer vector containing a short sequence of CDX1 siRNA (LS174T-siRNA) , or a pSilencer vector containing a scrambled siRNA sequence as a control (LS174T-Vec).

ORGANISM(S): Homo sapiens

PROVIDER: GSE14380 | GEO | 2009/01/13

SECONDARY ACCESSION(S): PRJNA111429

REPOSITORIES: GEO

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