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Clinical significance of gene signature generated from the grade of tumor budding in colorectal cancer

ABSTRACT: Tumor budding is a definite prognostic marker, but does not always show favorable reproducibility. We developed a new molecular signature related to tumor budding levels, a microscopic finding of dedifferentiation, using RNA extracted from the whole tissue section and disclosed its relevance to a high recurrence risk using an inhouse dataset and independent public datasets.

ORGANISM(S): Homo sapiens

PROVIDER: GSE143985 | GEO | 2020/04/24

REPOSITORIES: GEO

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