Transcriptomics

Dataset Information

0

High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier


ABSTRACT: Here, the effects of high glucose levels on influenza severity were investigated using an in vitro model of the pulmonary epithelial-endothelial barrier. We show that compared to low glucose levels, high glucose conditions prior to influenza A virus infection increased virus-induced barrier damage. Increased barrier damage was not associated with increased cell death nor increased virus replication, but rather an increased pro-inflammatory response in endothelial cells and the subsequent damage of the epithelial junctional complex.

ORGANISM(S): Homo sapiens

PROVIDER: GSE145232 | GEO | 2020/02/14

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA606471 | ENA
2023-05-23 | GSE203427 | GEO
2020-08-26 | GSE155120 | GEO
2022-02-24 | PXD025146 | Pride
2023-10-31 | GSE226679 | GEO
2021-09-09 | PXD018725 | Pride
2022-06-13 | PXD026625 | panorama
2012-10-29 | E-GEOD-32059 | biostudies-arrayexpress
2011-06-27 | E-GEOD-20257 | biostudies-arrayexpress
2013-09-11 | E-GEOD-50742 | biostudies-arrayexpress