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Liver mRNA expression in high fat diet fed mice with hepatic specific Slug knockout

ABSTRACT: Liver steatosis is a driving force for nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease, insulin resistance, and type 2 diabetes. Slug (also called Snai2 or Snail2) is a transcriptional regulator that may play a critical role in the regulation of liver function. To prove that, we used microarrays to detail the hepatic Slug regulated gene expression underlying liver steatosis and identified distinct pathways controlled by Slug during this process.

ORGANISM(S): Mus musculus

PROVIDER: GSE145404 | GEO | 2020/02/18

REPOSITORIES: GEO

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