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The Transcriptomic Responses of Atlantic Salmon (Salmo salar) to High Temperature Stress Alone, or in Combination with Moderate Hypoxia

ABSTRACT: In this study, we employed a 44K microarray approach to analyse the hepatic transcriptomic response of post smolt Atlantic salmon subjected to control conditions (12°C, ~100% air saturation), an incremental increase in temperature (12°C to 20°C; 1°C per week) under normoxia (~100% air saturation) or moderate hypoxia (~70% air saturation). Significance Analysis of Microarrays (FDR < 5%) identified 1900 and 2105 differentially expressed probes (DEPs) in salmon exposed to either Warm&Normoxic (WN) or Warm&Hypoxic (WH) conditions as compared with those maintained under control conditions (CT). Further, we found that heat stress alone or in combination with hypoxia caused most similar transcriptional responses and 1,111 (38%) DEPs were shared between WN and WH treatment groups. Consequently, in this study a unique set of 2,894 DEPs was determined.

ORGANISM(S): Salmo salar

PROVIDER: GSE146471 | GEO | 2021/02/16

REPOSITORIES: GEO

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