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Single cell RNA sequencing of dormant and proliferating prostate cancer cells from murine bone metastases

ABSTRACT: Using the immunocompetent bone-metastatic RM1 murine model of prostate cancer, the transriptomes of proliferating (PKH26-) eCFP+/luc2+ RM1 single cells (referred to as RM1536) were compared to dormant (PKH26+) RM1536 single cells dervied from bioluminescence imaging-verified bone metastases in mice at ~d16 post-intracardiac injection of PKH26 labelled RM1536 cells

ORGANISM(S): Mus musculus

PROVIDER: GSE147150 | GEO | 2020/10/01

REPOSITORIES: GEO

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Next generation sequencing of parental RM cells and RM1 cells derived bone and lung metastases for preliminary assessment of differential tumor cell gene expression in bone

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