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Transcriptomic analysis of KDM4B-mediated gene in C4-2B prostate cancer cells

ABSTRACT: Histone lysine demethylase KDM4B is often overexpressed in prostate cancer and links to poor survival outcome. Recent evidence suggests that KDM4B serves as a potential therapeutic target. The global transcriptomic analysis between control and KDM4B-knockdown C4-2B cells reveals the metabolic genes involved in Warburg effect are downregulated after knocking down the expression of KDM4B, indicating its role in tumor growth.

ORGANISM(S): Homo sapiens

PROVIDER: GSE147481 | GEO | 2023/03/24

REPOSITORIES: GEO

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