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Transcriptome after spatial exploration in CA1-specific brain tissue from wildtype and NEIL3-deficient mice

ABSTRACT: CA1-specific brain tissue from the hippocampal formation was isolated at baseline (homecage condition) and after a spatial exploration paradigm ("open field") in wildtype and NEIL3-deficient mice. NEIL3 is a DNA glycosylase potentially involved in transcription regulation. RNA was extracted and sequenced. Subsequently, these results were correlated to an extracellular live recording of pyramidal cell activity ("place cell recording") in the same genotypes.

ORGANISM(S): Mus musculus

PROVIDER: GSE148408 | GEO | 2021/11/01

REPOSITORIES: GEO

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