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Whole blood transcriptomics data in preterm birth and early preeclampsia

ABSTRACT: Maternal whole blood colected longitudinally were profiled using Affymetrix Human Transcriptome Arrays to evaluate prediction of gestational age in normal and complicated pregnancies and predict preterm birth. LMP is the date at the last menstrual period. Oper_LMP is the date at the last menstrual period with eventual adjustment based on ultrasound determination. Gestational age (GA) (weeks) is defined as (Date at sample - Oper_LMP)/7. For control pregnancies, SubGroup defines those with spontaneous labor at term (TL) as opposed with those delivered by cesarean section (TNL). Train is 1 if the sample was used in sub-challenge 1 in the training set as opposed to test set (0). D2 is 1 if the sample was used in the 2 interval prediction scenario, and if yes, it was assigned to the interval given by column D2Interval. D3 is 1 if the sample was used in the 3 interval prediction scenario, and if yes, it was assigned to the interval given by column D3Interval. DiagnosisGA is the gestational age at diagnosis with any disease indicated by the Group variable, and it is set to NA for normal pregnancies.

ORGANISM(S): Homo sapiens

PROVIDER: GSE149437 | GEO | 2021/05/24

REPOSITORIES: GEO

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