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Transcriptional profiling in adult onset ADPKD mouse model based on Pkd2 inactivation

ABSTRACT: We performed unbiased transcriptional profiling in an adult-onset Pkd2 mouse model at an early stage before cysts formed using as controls wild type and PC2+cilia double knockout mice which are protected from ADPKD. By a tripartite comparison, we identified differetially expressed genes which have significant different expression in Pkd2-only knockout with same direction of change from both wild type and Pkd2+Cilia double knockout.

ORGANISM(S): Mus musculus

PROVIDER: GSE149739 | GEO | 2020/12/31

REPOSITORIES: GEO

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