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Zebrafish embryonic mpeg+ macrophages

ABSTRACT: We used zebrafish lacking functional csf1r to unravel how and when csf1r is necessary for the development of early tissue macrophages from embryonic macrophages. Transcriptomic analysis of mpeg+ macrophages revealed that csf1r deficient macrophages show a macrophage transcriptome, but reduced expression of cell cycle and RNA/DNA metabolism related genes. Transcriptional changes over time were similar between wildtype controls als csf1r deficient embryonic macrophages.

ORGANISM(S): Danio rerio

PROVIDER: GSE149786 | GEO | 2020/05/05

REPOSITORIES: GEO

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