Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Zebrafish embryonic mpeg+ macrophages

ABSTRACT: Zebrafish embryonic mpeg+ macrophages

PROVIDER: PRJNA630160 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11684006_1.fastq.gz	Fastqsanger.gz
	SRR11684006_2.fastq.gz	Fastqsanger.gz
	SRR11684007_1.fastq.gz	Fastqsanger.gz
	SRR11684007_2.fastq.gz	Fastqsanger.gz
	SRR11684008_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Zebrafish embryonic mpeg+ macrophages

Project description:We used zebrafish lacking functional csf1r to unravel how and when csf1r is necessary for the development of early tissue macrophages from embryonic macrophages. Transcriptomic analysis of mpeg+ macrophages revealed that csf1r deficient macrophages show a macrophage transcriptome, but reduced expression of cell cycle and RNA/DNA metabolism related genes. Transcriptional changes over time were similar between wildtype controls als csf1r deficient embryonic macrophages.

2020-05-05 | GSE149786 | GEO

Zebrafish juvenile mpeg+ macrophages

Project description:Zebrafish juvenile mpeg+ macrophages

| PRJNA630163 | ENA

Zebrafish juvenile mpeg+ macrophages

Project description:We used zebrafish lacking functional csf1r or il34 to unravel how and when csf1r is necessary for macrophages. Transcriptomic analysis of mpeg+ macrophages isolated from juvenile fish revealed that csf1r deficient macrophages show a gross macrophage transcriptome, but reduced expression of engulfment related genes and increased expression of genes typical for metaphocytes.

2020-05-05 | GSE149787 | GEO

Zebrafish mpeg+ cells

Project description:Zebrafish mpeg+ cells

| PRJNA630158 | ENA

Zebrafish adult skin mpeg+ cells

Project description:Zebrafish adult skin mpeg+ cells

| PRJNA630162 | ENA

A robust method for performing 1H-NMR lipidomics in embryonic zebrafish

Project description:The embryonic zebrafish is an ideal system for lipid analyses with relevance to many areas of bioscience research, including biomarkers and therapeutics. Research in this area has been hampered by difficulties in extracting, identifying and quantifying lipids. We employed 1H-NMR at 700MHz to profile lipids in developing zebrafish embryos. The optimal method for lipidomics in embryonic zebrafish incorporated rapid lipid extraction using chloroform and an environment without oxygen depletion. Pools of 10 embryos gave the most acceptable signal-to-noise ratio, and the inclusion of chorions in the sample had no significant effect on lipid abundances. Embryos, bisected into cranial (head and yolk sac) and caudal (tail) regions, were compared by principal component analysis and analysis of variance.

2024-07-02 | MTBLS2396 | MetaboLights

Zebrafish adult skin mpeg+ cells

Project description:We compared hematopoietic and non-hematopoietic mpeg1.1+ cells from the skin of wild-type fish with non-hematopoietic cells from the skin of zebrafish lacking functional csf1r. We reval that non-hematopoietic mpeg1.1 cells from wild-type and csf1rDM fish show no major differences and likely represent metaphocytes, a newly characterized ectoderm-derived cell population in the skin. Both non-hematopoietic mpeg1.1+ cell populations from wild-type and csf1r mutatns show a major downregulations in canonical macrophages signature genes as compared to hematopoietic mpeg1.1 cells from wild-type fish.

2020-05-05 | GSE149788 | GEO

Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality

Project description:There are no described quality assurance mechanisms for newly formed stem cells. We observed intimate interactions between macrophages and blood stem cells in zebrafish embryos. Stressed stem cells were marked by surface Calreticulin, which stimulates macrophage interaction as an eat me signal. Macrophage-stem cell interactions either lead to removal of cytoplasmic material and stem cell proliferation or resulted in complete stem cell engulfment. Calreticulin knock down or embryonic macrophage depletion reduced the number of stem cell clones into adulthood. Our work supports a model in which embryonic macrophages determine hematopoietic clonality by monitoring stem cell quality.

2022-02-04 | MSV000088780 | MassIVE

Embryonic incubation temperature effect adult zebrafish

Project description:Embryonic incubation temperature effect adult zebrafish

| PRJNA495914 | ENA

Setaria italica strain:mPEG-2

Project description:Setaria italica strain:mPEG-2 Transcriptome or Gene expression

| PRJNA179367 | ENA