Distinct properties and functions of CTCF revealed by a rapidly inducible degron system [PRO-Seq]
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ABSTRACT: We coupled an auxin-induced degron (AID) system with precision nuclear run-on (PRO-seq). Oriented CTCF motifs in gene bodies are associated with transcriptional stalling in a manner ostensibly independent of bound CTCF. CTCF binding sites display highly variable resistance to degradation, with persistent sites displaying architectural related features.
ORGANISM(S): Mus musculus
PROVIDER: GSE150414 | GEO | 2021/02/23
REPOSITORIES: GEO
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