Transcriptional profiling of beta cell specific CD8 T cells from non-obese diabetic mice
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ABSTRACT: CD8 T cells specific for beta cell antigen islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) were identified and isolated with NRP-V7 tetramers from the pancreatic draining lymph node and pancreas of non-obese diabetic (NOD) mice and used for single-cell RNA-seq and VDJ-seq.
ORGANISM(S): Mus musculus
PROVIDER: GSE151652 | GEO | 2021/10/15
REPOSITORIES: GEO
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