Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Whole genome bisulfite sequencing from primate brains (orthologous region to human BA46)

ABSTRACT: We carried out cell-type specific whole genome bisulfite sequencing from primate brains (orthologous region to human BA46) that underwent fluorescence-activated nuclei sorting (FANS).

ORGANISM(S): Pan troglodytes Macaca mulatta

PROVIDER: GSE151768 | GEO | 2021/02/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Whole genome bisulfite sequencing from primate brains (orthologous region to human BA46)

Project description:Whole genome bisulfite sequencing from primate brains (orthologous region to human BA46)

| PRJNA637217 | ENA

Genome-wide profiling at single-nucleotide resolution of brain cell types in schizophrenia [WGBS]

Project description:We carried out cell-type specific whole genome bisulfite sequencing from BA46 that underwent fluorescence-activated nuclei sorting (FANS).

2019-06-25 | GSE107729 | GEO

Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

Project description:The foundation of many human-specific traits is likely established during early embryonic development. To understand these molecular processes, we compared gene expression dynamics in embryoid bodies (EBs) differentiated from iPSCs of four primate species: human, orangutan, cynomolgus, and rhesus macaque. We performed scRNA-seq on ∼ 85,000 cells after 8 and 16 days of EB differentiation, identifying diverse cell types across all three germ layers. To accurately compare cell types across species, we developed a semi-automated computational pipeline combining classification and label transfer across clusters to identify orthologous cell types. This approach allowed us to investigate cross-species reproducibility of marker genes, revealing that human markers were less effective in macaques, and vice versa. We found transcription factors to be the most conserved markers, highlighting their potential for cross-species studies. Overall, our study enhances the understanding of conserved and diverged molecular features in early primate development and we provide a well curated cell type reference for future in vitro studies using primates.

2024-11-15 | GSE280441 | GEO

Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

Project description:Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

| PRJNA1178606 | ENA

Extended Primate aCGH

Project description:Extended Primate aCGH

| PRJNA102527 | ENA

Primate Comparison Study

Project description:Primate Comparison Study

| PRJNA91975 | ENA

Primate malaria sequencing

Project description:Primate malaria sequencing

| PRJEB2081 | ENA

Extended Primate aCGH

Project description:This set includes individuals from 10 different primate species whose genomic DNA was used in an array-based comparative genomic hybridization (aCGH)using human cDNA microarrays to detect gene copy number variation across 10 primate species. An organism part comparison experiment design type compares tissues, regions, organs within or between organisms. Keywords: organism_part_comparison_design, array CGH Computed

2012-02-24 | E-GEOD-9028 | biostudies-arrayexpress

primate metagenome

Project description:Comparative Analysis of Primate Vaginal Microbiome

| PRJNA242706 | ENA

Cellular scaling rules for primate brains.

Project description:Primates are usually found to have richer behavioral repertoires and better cognitive abilities than rodents of similar brain size. This finding raises the possibility that primate brains differ from rodent brains in their cellular composition. Here we examine the cellular scaling rules for primate brains and show that brain size increases approximately isometrically as a function of cell numbers, such that an 11x larger brain is built with 10x more neurons and approximately 12x more nonneuronal cells of relatively constant average size. This isometric function is in contrast to rodent brains, which increase faster in size than in numbers of neurons. As a consequence of the linear cellular scaling rules, primate brains have a larger number of neurons than rodent brains of similar size, presumably endowing them with greater computational power and cognitive abilities.

| S-EPMC1805542 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data