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Expression data from DP cells in the thymus of SRSF1-null and wild type mice

ABSTRACT: iNKT cells are highly conserved innate-like T lymphocytes that develop from CD4+CD8+ DP cells. It remains largely unknown whether post-transcriptional regulation has critical roles in iNKT cells. Here we show conditional deactivation of SRSF1 in DP thymocytes impaired iNKT cell development and survival in a cell-intrinsic manner.

ORGANISM(S): Mus musculus

PROVIDER: GSE156013 | GEO | 2022/08/11

REPOSITORIES: GEO

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