Transcriptomics

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Regional specialization and fate specification of mesenchymal stromal cells in skeletal development [scRNA-seq]


ABSTRACT: To identify cellular heterogeneity and molecular signatures of bone marrow stromal (BMSCs) cells, we performed scRNA-seq of non-hematopoietic stromal cells from 3-week-old mice. In addition, to gain further insight into MSC differentiation in vivo, Pdgfrb-CreERT2 Rosa26-mTmG (Pdgfrb-Cre R26-mT/mG) double transgenic mice were treated with tamoxifen at P1-3 and sacrificed at P21 for the isolation of GFP+ cells from long bone followed by scRNA-seq analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE156635 | GEO | 2021/07/27

REPOSITORIES: GEO

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