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Lnc-Cxcl2 suppressed Cxcl2 expression in mouse lung epithelial cells

ABSTRACT: In this study, we performed RNA-seq in GFP-VSV infected mouse lung epithelial cell lines (MLE-12 cells) and found that the expression of a non-coding RNA was increased upon VSV infection in Cxcl2 locus, which we termed it as lnc-Cxcl2. We further detected the function of lnc-Cxcl2 by performing transcriptome analysis in lnc-Cxcl2-deficient MLE-12 cells with and without VSV infection, and found that lnc-Cxcl2 suppressed Cxcl2 expression in MLE-12 cells with and without VSV infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE156949 | GEO | 2021/09/26

REPOSITORIES: GEO

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