Transcriptomics

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Genome-wide transcripts from X chromosome by high throughput sequencing [RNA-Seq]


ABSTRACT: We analyzed a transcriptional landscape of the Xi during somatic cell reprogramming of female mouse cells. We use MEFs from hybrid embryos by crossing male Mus spretus and female Mus musculus domesticus C57BL/6J to monitor allele-specific transcripts from the Xi. We could capture the earliest phase of X chromosome reactivation and found that a subset of genes clustered near the centromere display an early reactivation on the Xi.

ORGANISM(S): Mus musculus

PROVIDER: GSE157481 | GEO | 2022/01/01

REPOSITORIES: GEO

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