Proteomics

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Variation in mouse chemical signals is genetically controlled and environmentally modulated


ABSTRACT: Urine proteomes of the house mouse (Mus musculus musculus, M. m. domesticus, M. m. castaneus).

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Mus Musculus Castaneus Mus Musculus Domesticus Mus Musculus Musculus

TISSUE(S): Urine

SUBMITTER: Pavel Stopka  

LAB HEAD: Pavel Stopka

PROVIDER: PXD037086 | Pride | 2023-07-20

REPOSITORIES: Pride

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Publications

Variation in mouse chemical signals is genetically controlled and environmentally modulated.

Stopková Romana R   Matějková Tereza T   Dodoková Alica A   Talacko Pavel P   Zacek Petr P   Sedlacek Radislav R   Piálek Jaroslav J   Stopka Pavel P  

Scientific reports 20230526 1


In most mammals and particularly in mice, chemical communication relies on the detection of ethologically relevant fitness-related cues from other individuals. In mice, urine is the primary source of these signals, so we employed proteomics and metabolomics to identify key components of chemical signalling. We show that there is a correspondence between urinary volatiles and proteins in the representation of genetic background, sex and environment in two house mouse subspecies Mus musculus muscu  ...[more]

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