Epigenome analysis of brochoscopic paired biopsy specimens from tumoral sites and the contralateral bronchus.
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ABSTRACT: Genome wide DNA methylation profiling of brochoscopic paired biopsy samples from tumoral sites and the contralateral bronchus (controls). The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs in bronchoscopic biopsy samples. In 37 patients (74 samples) a difinite histological diagnosis could be reached. In the remaining 36 samples the diagnosis remained indefinite, the assumption of the pathologists is stated.
ORGANISM(S): Homo sapiens
PROVIDER: GSE158075 | GEO | 2021/03/02
REPOSITORIES: GEO
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