ATAC-sequencing data for 923 enhancer deletion newborn mouse keratinocytes

ABSTRACT: We examined the ATAC-seq chromatin profiles of epidermis from newborn CRISPR-edited mice that have the 923 enhancer located within the Epidermial Differentiation Complex deleted. We examined two independent deletion lines, 923del and 923large, homozygous mutants, as well as wild type mice. We find overall there are not many differences in chromatin accessibility upon the loss of the 923 enhancer, though there are a few peaks of less accessible DNA within the EDC and more accessible DNA just outside the EDC.

ORGANISM(S): Mus musculus

PROVIDER: GSE158868 | GEO | 2020/10/30

REPOSITORIES: GEO