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Generation and characterization of human iPSC-derived microglia-like cells for the use in drug discovery

ABSTRACT: For the development of human cellular models of microglial that allow for exploring disease underlying mechanisms and testing potential therapeutic compounds on a larger scale we generated microglia-like cells from human induced pluripotent stem cells (iPSC) and performed subsequent phenotypic and functional testing and validation by using bulk RNASeq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE159108 | GEO | 2021/02/24

REPOSITORIES: GEO

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Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Bulk RNAseq]

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