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IPSC-derived Human Intestinal Organoids are permissive to SARS-CoV-2 infection

ABSTRACT: We performed transcriptomic profiling of cells derived from human induced pluripotent stem cells (iPSCs) using a directed differentiation protocol to generate mesenchyme free, regionally patterned intestinal organoids. These organoids were then infected with SARS-CoV-2, and sequencing was performed 1 and 4 days post infection

ORGANISM(S): Homo sapiens

PROVIDER: GSE159201 | GEO | 2021/04/20

REPOSITORIES: GEO

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