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Ints11 is essential for normal function of hematopoietic stem/progenitor cells [RNA-seq]

ABSTRACT: To investigate the role of INTS11 in normal hematopoiesis, Ints11 conditional KO mouse model was generated. We purified the Lin-cKit+ cells from bone marrow of WT and Ints11 KO mice and studied the differentially expressed genes due to the Ints11 loss.

ORGANISM(S): Mus musculus

PROVIDER: GSE159403 | GEO | 2021/09/22

REPOSITORIES: GEO

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Ints11 is essential for normal function of hematopoietic stem/progenitor cells [ChIP-Seq]

Project description:To investigate the role of INTS11 in normal hematopoiesis, Ints11 conditional KO mouse model was generated. We purified the Lin-cKit+ cells from bone marrow of WT and Ints11 KO mice and performed the ChIP-seq using different histone modifications to invesigate the gene regulation.

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Ints11 is essential for normal function of hematopoietic stem/progenitor cells [single-cell RNA-seq]

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Bromodomain member BRD4 is required for hematopoietic stem cell functions (RNA-Seq)

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2012-09-19 | E-GEOD-32265 | biostudies-arrayexpress

Bromodomain member BRD4 is required for hematopoietic stem cell functions (scRNA-Seq)

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Ints11 is essential for normal function of hematopoietic stem/progenitor cells

Project description:Ints11 is essential for normal function of hematopoietic stem/progenitor cells

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