MiRNA sequencing signature in acquired radioresistant and normal colorectal cancer cells.
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ABSTRACT: To explore the mechanisms underlying the radioresistance of colorectal cancer, we established specifically radioresistant HCT116 cell line (HCT116-R cells) and RKO cell line (RKO-R cells) derived from HCT116 and RKO cell lines by repeatedly exposing to multi-fractionated irradiation. Then, the aberrantly expressed miRNA were detected by miRNA sequencing and their bioinformatics were analyzed.
ORGANISM(S): Homo sapiens
PROVIDER: GSE159528 | GEO | 2021/01/10
REPOSITORIES: GEO
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