Transcriptomics

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Patient-derived brain organoids uncover reversible cellular abnormalities in Pitt-Hopkins Syndrome III


ABSTRACT: We evaluate cellular phenotypic abnormalities and alterations in molecular pathways due to mutations in the gene TCF4 in cells derived from Pitt-Hopkins patients, in comparison with respective controls (parents).

ORGANISM(S): Homo sapiens

PROVIDER: GSE159860 | GEO | 2022/03/02

REPOSITORIES: GEO

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