Genomics

Dataset Information

0

Identify genomic binding sites of Tfcp2l1 in mouse embryonic stem cells grown in 2i medium


ABSTRACT: Mouse embryonic stem cells (ESCs) grown in the 2i (an ERK inhibitor, PD0325901, and a GSK-3b inhibitor, CHIR99021) mimic pluripotent epiblasts in preimplantation blastocysts. Tfcp2l1 is a transcription factor highly expressed in ESCs grown in the 2i medium, suggesting that it plays in important role in ESC biology. To search for the putative role(s) of Tfcp2l1 in ESCs, we plan to use an integrated genomic approach--combing RNA-seq and ChIP-seq--to identify the direct targets of Tfcp2l1 in ESCs. ChIP-seq is used to identify the genomic bindings sites of Tfcp2l1 in ESCs grown in the 2i medium.

ORGANISM(S): Mus musculus

PROVIDER: GSE159877 | GEO | 2021/03/01

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2021-03-01 | GSE159937 | GEO
| PRJNA670915 | ENA
| PRJNA670706 | ENA
2019-11-08 | PXD015635 | Pride
2018-11-07 | PXD009217 | Pride
2013-04-26 | GSE46369 | GEO
2013-03-01 | E-GEOD-43421 | biostudies-arrayexpress
2018-11-21 | PXD007154 | Pride
2013-04-26 | E-GEOD-46369 | biostudies-arrayexpress
2017-07-27 | GSE82313 | GEO