Using a Zebrafish Model to Identify Cellular Responses to Uropathogenic E. coli Bacteremia
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ABSTRACT: Urinary tract infections (UTIs) are the second most common infections encountered in the pediatric population, second only to respiratory tract infections. UTIs are also a major cause of morbidity and mortality. UTIs can often ascend causing infection in the upper urinary tract or even progress to bacteremia or urosepsis. Urosepsis accounts for 10-30% of septic shock cases and Uropathogenic E.coli (UPEC) is responsible for almost 75% of cases. Therefore, increased understanding of the effects of urosepsis at the cellular and organ specific level will provide the foundation for improvements in clinical care.
ORGANISM(S): Danio rerio
PROVIDER: GSE160038 | GEO | 2020/10/26
REPOSITORIES: GEO
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