Transcriptomics

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Mutated IGHV3-23 CLL


ABSTRACT: Expression of stereotyped B cell receptors (BCR), i.e. non-random combinations of immunoglobulin heavy-chain variable (IGHV) genes, complementarity-determining region-3 (HCDR3), and IGV light chains, identifies discrete clusters and represents a peculiar feature of chronic lymphocytic leukemia (CLL). Expression of IGHV3-23 characterized a CLL subset with peculiar molecular and clinical features.

ORGANISM(S): Homo sapiens

PROVIDER: GSE16065 | GEO | 2009/06/13

SECONDARY ACCESSION(S): PRJNA115487

REPOSITORIES: GEO

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