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Histone H2B.8 compacts flowering plant sperm through chromatin phase separation

ABSTRACT: We characterised a sperm-expressed histone variant, H2B.8 in Arabidopsis by performing ChIP-seq, RNA-seq, and Hi-C. The data show that H2B.8 is exclusively deposited to unexpressed euchromatin and that gene expression is not significantly affected either by h2b.8 mutation in sperm or overexpression in soma. The deposition of H2B.8increases the contact probability of short range intrachromosomal interactions and contacts between pericentomeric regions and chromosome arms of different chromosomes.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE161366 | GEO | 2022/07/26

REPOSITORIES: GEO

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Histone H2B.8 compacts flowering plant sperm through chromatin phase separation

Project description:Histone H2B.8 compacts flowering plant sperm through chromatin phase separation

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