Transcriptomics

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Differential gene expression between immature and mature enterocyte like-Caco2 cells


ABSTRACT: Human Caco2 intestinal cells represent an in vitro model of human enterocytes. These cells are able to acquire a phenotype of mature polarized enterocytes when they are maintained in transwell culture system for 2-3 weeks.The goal of this study was to analyze the differences in mRNA expression profiles between Caco2 cells at a early stage of their differentiation (day 8) and at a more advanced stage of their differenciation (day 16) into absorptive enterocytes. A 3' Digital Gene expression (DGE) RNA sequencing was performed to determine mRNA expression profiles.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162633 | GEO | 2021/09/22

REPOSITORIES: GEO

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