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Epithelial miR-141 regulates IL-13-induced airway mucus production

ABSTRACT: We performed RNA sequencing of gene expression in primary human bronchial epithelial cells that have undergone CRISPR/Cas9-based targeting of MIR141. The goal was to identify the role of miR-141 in goblet cell mucus production. CRISPR-targeted cells were differentiated at air-liquid-interface and stimulated with IL-13 to induce goblet cell hyperplasia.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162696 | GEO | 2020/12/05

REPOSITORIES: GEO

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Epithelial miR-141 regulates IL-13-induced airway mucus production

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| S-EPMC8021117 | biostudies-literature

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