Expression data from stabilized epithelial pancreatic cancer cells
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ABSTRACT: Pancreatic ductal adenocarcinoma is therapeutically recalcitrant and metastatic. Epithelial to mesenchymal transition (EMT) is associated with metastasis, however, a causal connection needs further unraveling. We explored the impact of stabilized EMT states on PDAC metastasis through the use of genetically-engineered mouse models that exhibit a stabilized epithelial phenotype through the deletion of EMT-driving transcription factors Snail and Twist together We examined the cancer cell-intrinsic pathways associated with stabilized epithelial pancreatic adenocarcinoma cells.
ORGANISM(S): Mus musculus
PROVIDER: GSE164612 | GEO | 2021/04/13
REPOSITORIES: GEO
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