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Transcriptional and genomic occupancy profiling from MLX WT and MLX knockout mouse tissues.

ABSTRACT: We generated mice null for MAX-like Protein X (MLX), encoded by Mlx. All male mice are sterile. We profiled testes tissue from WT versus KO mice by RNA-Seq. We performed ChIP-Seq on WT and KO testes for MLX and MAX, as well as ChIP-Seq for MLX and MAX from primary B220+ splenic B cells, and ChIP-Seq for MLX, MAX and MNT from 3T3 cell lines derived from WT and KO embryos.

ORGANISM(S): Mus musculus

PROVIDER: GSE165820 | GEO | 2021/07/31

REPOSITORIES: GEO

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The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling

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