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Characterization of the coding and noncoding transcriptome in undifferentiated and differentiating of WT and Notch1-deficient mouse embryonic stem cells

ABSTRACT: RNA (poly(A)+ fraction)was isolated from WT and Notch1-deleted mouse embryonic stem cells at the undifferetiated and differentiated (6 days; using the hanging drop model) state. Profiling of the transcritome at these two stages of differentiation using deep RNA sequencing allows identifying modulated coding and noncoding transcripts upon induction of differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE166952 | GEO | 2021/09/01

REPOSITORIES: GEO

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