ChIP-on-chip from acute myeloid leukemia cell lines and clinical samples for H3K4me3, H3K27me3, and EZH2
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ABSTRACT: Histone modifcations at the p15INK4b gene were compared in sample with p15INK4b DNA methylation vs. samples with no DNA methylation AML clinical samples without DNA methylation exhibit bivalent histone modifications at p15INK4b, while clinical samples with DNA methylation display lower H3K4me3 and retain H3K27me3
ORGANISM(S): Homo sapiens
PROVIDER: GSE16730 | GEO | 2009/08/15
SECONDARY ACCESSION(S): PRJNA117419
REPOSITORIES: GEO
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