Transcriptomics

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The Tec kinase ITK optimizes differential NFAT, NF-κB, and Erk1/2 signaling to regulate graded gene induction in mouse CD8+ T cells [RNA-seq]


ABSTRACT: In this study we generated SMART-seq cDNA libraries from mouse CD8+ OT-I T cells that were stimulated with WT splenocytes loaded with OVA peptide or OVA peptide variants, with or without presence of ITK inhibitor PRN-694 at early time points (0, 30min, 60min, or 120min).

ORGANISM(S): Mus musculus

PROVIDER: GSE167303 | GEO | 2021/02/23

REPOSITORIES: GEO

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