Transcriptome profiling of muscle stem cells from control, mdx and Sirt6 knockout on mdx background mice
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ABSTRACT: In this study, Pax7-Cre mediated inactivation of Sirt6 in mdx mice resulted in profound improvement of the mdx phenotype at the functional level. To study the underlying molecular mechanisms we performed RNA-seq of MuSCs from control, mdx and Sirt6mKO/mdx mice.
ORGANISM(S): Mus musculus
PROVIDER: GSE168983 | GEO | 2022/05/12
REPOSITORIES: GEO
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