Translocase malfunction causes extracellular protein translocation stress ( EPTS) in Streptomyces lividans

ABSTRACT: The genomic and proteomic analyses of Streptomyces lividans strains deficient in the major signal peptidase SipY or in the translocase complex protein SecG resulted in a set of genes being equally regulated. These genes are apparently responsible for the common deficiencies in extracellular protein production and sporulation shared by both mutant strains, constituting a cellular response to the stress caused by the potential malfunction of the translocase complex, which we have named “extracellular protein translocation stress (EPTS)”.

ORGANISM(S): Streptomyces coelicolor A3(2) Streptomyces lividans

PROVIDER: GSE17012 | GEO | 2012/05/04

SECONDARY ACCESSION(S): PRJNA117755

REPOSITORIES: GEO