Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Evaluating the H2O2-induced tRNA expressions change in Streptococcus oligofermentans

ABSTRACT: The tRNA gene expression change was evaluated by whole genomic microarray chip in Streptococcus oligofermentans challenged by H2O2.

ORGANISM(S): Streptococcus cristatus

PROVIDER: GSE171631 | GEO | 2024/04/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Evaluating the H2O2-induced tRNA expressions change in Streptococcus oligofermentans

Project description:Evaluating the H2O2-induced tRNA expressions change in Streptococcus oligofermentans

| PRJNA720380 | ENA

tRNA profiling of MCF10A cells after H2O2 stress

Project description:We report the changes in tRNA abundance as measured by tRNA profiling after cells have been exposed to oxidative stress by H2O2.

2019-09-25 | GSE120381 | GEO

tRNA profiling of MCF10A cells after H2O2 stress

Project description:tRNA profiling of MCF10A cells after H2O2 stress

| PRJNA492919 | ENA

Transcriptome comparison of the Streptococcus pneumoniae D39∆tpxD treated with 1mM to 0mM H2O2

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39∆tpxD grown in THY medium till OD620=0.25 and then treated with or without 1mM H2O2 for 40mins.

2017-07-27 | GSE65156 | GEO

Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type treated with 1mM to with 0mM H2O2

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 wild-type grown in THY medium till OD620=0.25 and then treated with or without 1mM H2O2 for 40mins.

2017-07-27 | GSE65155 | GEO

The impact of H2O2 exposure on the transcriptome of Streptococcus mutans wild type and perR mutant strains

Project description:H2O2 is an oxidative stress agent known to trigger an upregulation in expression of detoxification genes in Streptococcus mutans. Following discovery of a spontaneously-occurring perR mutation, we wanted to compare the transcriptomic responses of H2O2 exposure in S. mutans strains bearing an intact perR or a perR deletion.

2020-09-17 | GSE158080 | GEO

smRNA sequencing of MCF10A cells after H2O2 stress

Project description:We report the changes in tRNA fragment abundance as measured by small RNA sequencing after cells have been exposed to oxidative stress by H2O2.

2019-09-25 | GSE120382 | GEO

The impacts of the Spx regulator and H2O2 stress on the transcriptome of Streptococcus mutans

Project description:As a resident of the oral cavity, Streptococcus mutans must withstand a variety of stresses, including oxidative stress. Previously, we reported the identification of two Spx homologues (SpxA1 and SpxA2) in Streptococcus mutans that appear critical in the ability of the microbe to tolerate oxidative stresses; SpxA1 was shown to play a primary role in activation of detoxification strategies whereas SpxA2 served as a secondary activator. Here, we used RNA deep sequencing (RNA-Seq) to examine the transcriptional changes associated with H2O2 stress in the parent S. mutans strain UA159 and to compare the peroxide-stress transcriptome of UA159 with its Δspx derivatives. The transcriptome data confirmed the relationship between SpxA1 and genes typically associated with oxidative stress responses, but also identified new genes and metabolic pathways that are activated during peroxide stress, also in an SpxA1-dependent manner.

2017-05-08 | GSE98526 | GEO

spxA1-null mutant of Streptococcus sanguinis SK36

Project description:Transcriptional profiling of the spxA1-null mutant of Streptococcus sanguinis SK36 compared with wild type. The spxA1 gene was inactivated in Streptococcus sanguinis SK36, and the mutant demonstrated opaque colony morphology, reduced hydrogen peroxide (H2O2) production, and reduced antagonistic activity against Streptococcus S. mutans UA159 both on plates and in liquid media. The mutant also showed decreased tolerance to high temperature, and acidic and oxidative stresses. Complementation of the ΔspxA1 mutant with spxA1 restored colony morphology, H2O2 production and stress tolerance to the ΔspxA1 mutant. The mutant also exhibited an ~5-fold reduction in competitiveness in an animal model of endocarditis, indicating the involvement of SpxA1 in endocarditis virulence. Microarray studies revealed that a number of SpxA1-upregulated genes are involved in oxidative stress. The expression of spxB and nox (which encode pyruvate oxidase and NADH oxidase, respectively, and are involved in H2O2 production and nox involved virulence) significantly decreased in ΔspxA1 compared with the wild type. This may be at least partly responsible for the decreased H2O2 production and reduced virulence in the ΔspxA1 mutant because spxB and nox were involved in H2O2 production and nox involved virulence.

2011-12-08 | GSE34203 | GEO

spxA1-null mutant of Streptococcus sanguinis SK36

2011-12-08 | E-GEOD-34203 | biostudies-arrayexpress