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Alterations in chromosome spatial compartmentalization classify prostate cancer progression [Hi-C]

ABSTRACT: Through a systematic analysis of chromosome conformation capture in a cohort of cells that model cancer progression, San Martin et.al. find that rearrangement of the 3D genome structure in prostate cancer is a potential mechanism for disease exacerbation and that genome-wide compartment identity can classify cancer according to progression

ORGANISM(S): Homo sapiens

PROVIDER: GSE172097 | GEO | 2021/05/01

REPOSITORIES: GEO

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