Transcriptomics

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Comparative transcriptome analysis of dedifferentiation in porcine mature adipocytes and follicular granulosa cells


ABSTRACT: Cellular dedifferentiation signifies the withdrawal of cells from a specific differentiated state into a ‘stem cell’-like undifferentiated state. However, the mechanism of dedifferentiation remains obscure. We showed that mature adipocytes (MA) and follicular granulosa cells (GC), which have distinct functions in vivo, can dedifferentiate during culture in vitro and acquire multipotency. We investigated the dedifferentiation mechanism of MA and GC using global gene expression analyses.

ORGANISM(S): Sus scrofa

PROVIDER: GSE17264 | GEO | 2011/03/10

SECONDARY ACCESSION(S): PRJNA119169

REPOSITORIES: GEO

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