Regulatory T cell-mediated resolution of lung injury: Identification of potential target genes via expression profiling
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ABSTRACT: We examined early and late gene expression changes using the IT LPS model of Acute Lung Injury (ALI). In this model, injury peaks at day 4 and is almost completely resolved by day 10 in wild type (WT) C57BL/6 mice. In contrast to the pattern in WT mice, lymphocyte-deficient Rag-1 -/- mice exhibit strikingly delayed resolution despite similar initial injury.
ORGANISM(S): Mus musculus
PROVIDER: GSE17355 | GEO | 2009/12/31
SECONDARY ACCESSION(S): PRJNA119073
REPOSITORIES: GEO
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