Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNAseq analysis of CC F2 female mice at day3 after infection with Ebola virus

ABSTRACT: F2 female mice were generated from a cross of two collaborative cross (CC) strains, CC011 x CC074. These mice were infected with Ebola virus and liver samples were prepared at day three after infection. RNA from the livers were prepared and subjected to RNAseq analysis. This data set can be combined with data from GSE165142, in which female mice from the same cross were infected with Ebola virus, and liver samples were prepared at day six after infection. Results: Variations in gene expression levels that may be perdictive for severity

ORGANISM(S): Mus musculus

PROVIDER: GSE173914 | GEO | 2022/08/31

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNAseq analysis of CC F2 female mice at day3 after infection with Ebola virus

Project description:RNAseq analysis of CC F2 female mice at day3 after infection with Ebola virus

| PRJNA727545 | ENA

Transcriptional Correlates of Tolerance and Lethality from Mouse Models Predict Ebola Virus Disease Outcome

Project description:We report comparative outcome-dependent transcriptional profiles from spleen and liver from Collaborative Cross mice infected with mouse-adapted Ebola virus (MA-EBOV).

2019-12-01 | GSE130629 | GEO

IHH microRNA response to genetically-reconstructed Zaire Ebola viruses [miRNA]

Project description:The purpose of this experiment was to obtain samples for mRNA analysis in IHH cells infected with Zaire Ebola virus and mutants: Zaire Ebola virus: This wild-type Ebola virus - strain Mayinga - was isolated from a fatal human case in Zaire (now known as the Democratic Republic of Congo) in 1976 Zaire Ebola virus, VP35 R312A possesses a R312A mutation in the VP35 protein. Zaire Ebola virus, delta sGP. Lacks the ability to produce non-structural protein, the secreted glycoprotein (sGP). Zaire Ebola virus, delta mucin. Lacks the mucin-like domain (MLD), which contains both N-linked and O-linked glycosylation sites, for the glycoproteins. Overview of Experiment: Cells: Immortalized Human Hepatocytes (IHH); seed 60,000 cells per well in a 24-well plate. Infected with a multiplicity of infection (MOI) of 0.5. After infection, 3x wash with PBS and replace with 5% FCS DMEM without NaPyr or NEAA. Time matched mocks done in triplicate from same cell stock as rest of samples. Time Points = 0, 6, 12, 24, 48, and 72 hrs post infection in triplicate.

2015-06-18 | E-GEOD-69943 | biostudies-arrayexpress

IHH mRNA response to genetically-reconstructed Zaire Ebola viruses [mRNA]

2015-06-18 | E-GEOD-69942 | biostudies-arrayexpress

RNAseq analysis of CC F2 female mice after infection with Ebola virus

Project description:RNAseq analysis of CC F2 female mice after infection with Ebola virus

| PRJNA693338 | ENA

IHH microRNA response to genetically-reconstructed Zaire Ebola viruses [miRNA]

2015-06-18 | GSE69943 | GEO

IHH mRNA response to genetically-reconstructed Zaire Ebola viruses [mRNA]

2015-06-18 | GSE69942 | GEO

Human U937 cell transcriptome response to Zaire Ebola virus wild-type in the delta-VP30 background and delta-mucin virus

Project description:The purpose is to obtain samples for mRNA analysis in human U937 cells infected with Zaire Ebola virus wild-type in the deltaVP30 background and delta-mucin virus. Human U937 cells (monocyte-like) expressing the Ebola VP30 protein were infected with Zaire Ebola virus wild-type (wild) in the delta-VP30 background and delta-mucin virus (encodes a GP lacking the mucin domain) (mucin). Infected samples were collected in quintuplet; time-matched mocks were collected in quintuplet in parallel with infected samples. Time points: 0, 8, 18, and 30 h post-infection.

2016-05-19 | E-GEOD-80832 | biostudies-arrayexpress

Global transcriptomic analysis of iPSC-derived hepatocytes infected with Ebola virus (EBOV)

Project description:We performed transcriptomic analysis of a time course of Ebola virus (EBOV) iPSC-derived hepatocytes. Mock infected and EBOV infected hepatocytes were harvested 1, 2, 3, and 7 days post-infection for analysis. Hepatocytes were infected with EBOV at a multiplicity of infection of 10.

2022-09-01 | GSE184639 | GEO

Ebola virus

Project description:Ebola virus Genome sequencing

| PRJNA353605 | ENA